Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-LSM8 (1-96) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
LSM8 |
Gene ID: |
51691 |
Uniprot ID: |
LSM8_HUMAN |
Immunogen Region: |
1-96 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-96 of human LSM8 (NP_057284.1). |
Immunogen Sequence: |
MTSALENYINRTVAVITSDG RMIVGTLKGFDQTINLILDE SHERVFSSSQGVEQVVLGLY IVRGDNVAVIGEIDEETDSA LDLGNIRAEPLNSVAH |
Function | Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. |
Protein Name | U6 Snrna-Associated Sm-Like Protein Lsm8 |
Database Links | Reactome: R-HSA-72163 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-U6 Snrna-Associated Sm-Like Protein Lsm8 antibodyAnti-LSM8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance