• Western blot analysis of various lysates using KIRREL2 Rabbit polyclonal antibody (STJ115096) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-KIRREL2 antibody (21-220) (STJ115096)

SKU:
STJ115096

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIRREL2
Gene ID: 84063
Uniprot ID: KIRR2_HUMAN
Immunogen Region: 21-220
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 21-220 of human KIRREL2 (NP_954649.3).
Immunogen Sequence: GPSPHFLQQPEDLVVLLGEE ARLPCALGAYWGLVQWTKSG LALGGQRDLPGWSRYWISGN AANGQHDLHIRPVELEDEAS YECQATQAGLRSRPAQLHVL VPPEAPQVLGGPSVSLVAGV PANLTCRSRGDARPTPELLW FRDGVLLDGATFHQTLLKEG TPGSVESTLTLTPFSHDDGA TFVCRARSQALPTGRDTAIT
Tissue Specificity Highly expressed in beta-cells of the pancreatic islets.
Post Translational Modifications N-glycosylated. The extracellular domain is cleaved leading to the generation of a soluble fragment and a membrane-bound C-terminal fragment, which is further cleaved by gamma-secretase.
Function May regulate basal insulin secretion.
Protein Name Kin Of Irre-Like Protein 2
Kin Of Irregular Chiasm-Like Protein 2
Nephrin-Like Protein 3
Database Links Reactome: R-HSA-373753
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Localized Along The Sites Of The Cell Contacts
Colocalizes With E-Cadherin And Beta-Catenin
Alternative Antibody Names Anti-Kin Of Irre-Like Protein 2 antibody
Anti-Kin Of Irregular Chiasm-Like Protein 2 antibody
Anti-Nephrin-Like Protein 3 antibody
Anti-KIRREL2 antibody
Anti-NEPH3 antibody
Anti-UNQ5827 antibody
Anti-PRO19646 antibody

Information sourced from Uniprot.org

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