| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KIR3DL2 (361-455) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KIR3DL2 |
| Gene ID: |
3812 |
| Uniprot ID: |
KI3L2_HUMAN |
| Immunogen Region: |
361-455 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 361-455 of human KIR3DL2 (NP_006728.2). |
| Immunogen Sequence: |
YRWCSNKKNAAVMDQEPAGD RTVNRQDSDEQDPQEVTYAQ LDHCVFIQRKISRPSQRPKT PLTDTSVYTELPNAEPRSKV VSCPRAPQSGLEGVF |
| Tissue Specificity | Expressed in astrocytes. |
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl2 antibodyAnti-Cd158 Antigen-Like Family Member K antibodyAnti-Natural Killer-Associated Transcript 4 antibodyAnti-Nkat-4 antibodyAnti-P70 Natural Killer Cell Receptor Clone Cl-5 antibodyAnti-P70 Nk Receptor Cl-5 antibodyAnti-Cd Antigen Cd158k antibodyAnti-KIR3DL2 antibodyAnti-CD158K antibodyAnti-NKAT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
