• Western blot analysis of extracts of various cell lines, using KIR2DL1 antibody (STJ24315) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-KIR2DL1 antibody (22-270) (STJ24315)

SKU:
STJ24315

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KIR2DL1 (22-270) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIR2DL1
Gene ID: 3802
Uniprot ID: KI2L1_HUMAN
Immunogen Region: 22-270
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-270 of human KIR2DL1 (XP_003403624.1).
Immunogen Sequence: HEGVHRKPSLLAHPGRLVKS EETVILQCWSDVRFEHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHECRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSKTERM FHHVGQACLKLPTSSDPTV
Tissue Specificity Expressed by NK cells.
Function Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
Protein Name Killer Cell Immunoglobulin-Like Receptor 2dl1
Cd158 Antigen-Like Family Member A
Natural Killer-Associated Transcript 1
Nkat-1
P58 Natural Killer Cell Receptor Clones Cl-42/47.11
P58 Nk Receptor Cl-42/47.11
P58.1 Mhc Class-I-Specific Nk Receptor
Cd Antigen Cd158a
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Killer Cell Immunoglobulin-Like Receptor 2dl1 antibody
Anti-Cd158 Antigen-Like Family Member A antibody
Anti-Natural Killer-Associated Transcript 1 antibody
Anti-Nkat-1 antibody
Anti-P58 Natural Killer Cell Receptor Clones Cl-42/47.11 antibody
Anti-P58 Nk Receptor Cl-42/47.11 antibody
Anti-P58.1 Mhc Class-I-Specific Nk Receptor antibody
Anti-Cd Antigen Cd158a antibody
Anti-KIR2DL1 antibody
Anti-CD158A antibody
Anti-NKAT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance