• Western blot analysis of extracts of various cell lines, using KIF3B antibody (STJ118199) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-KIF3B antibody (663-747) (STJ118199)

SKU:
STJ118199

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KIF3B (663-747) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KIF3B
Gene ID: 9371
Uniprot ID: KIF3B_HUMAN
Immunogen Region: 663-747
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 663-747 of human KIF3B (NP_004789.1).
Immunogen Sequence: LELDMPSRTTRDYEGPAIAP KVQAALDAALQDEDEIQVDA SSFESTANKKSKARPKSGRK SGSSSSSSGTPASQLYPQSR GLVPK
Function Microtubule-based molecular motor that transport intracellular cargos, such as vesicles, organelles and protein complexes. Uses ATP hydrolysis to generate force to bind and move along the microtubule. Plays a role in cilia formation. Involved in photoreceptor integrity and opsin trafficking in rod photoreceptors. Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit GRIN2A into neuronal dendrites.
Protein Name Kinesin-Like Protein Kif3b
Hh0048
Microtubule Plus End-Directed Kinesin Motor 3b Cleaved Into - Kinesin-Like Protein Kif3b - N-Terminally Processed
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-2132295
Reactome: R-HSA-5620924
Reactome: R-HSA-6811434
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Cilium
Dendritic Spine
Alternative Antibody Names Anti-Kinesin-Like Protein Kif3b antibody
Anti-Hh0048 antibody
Anti-Microtubule Plus End-Directed Kinesin Motor 3b Cleaved Into - Kinesin-Like Protein Kif3b - N-Terminally Processed antibody
Anti-KIF3B antibody
Anti-KIAA0359 antibody

Information sourced from Uniprot.org

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