| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily S member 1 channel alpha subunit 1 (470-550 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNS1 |
| Gene ID: |
3787 |
| Uniprot ID: |
KCNS1_HUMAN |
| Immunogen Region: |
470-550 aa |
| Specificity: |
KCNS1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 470-550 |
| Function | Potassium channel regulatory subunit that modulate the delayed rectifier voltage-gated potassium channel activity of KCNB1 and KCNB2 by altering their kinetics, expression levels, and shifting the half-inactivation potential to more polarized values. While it does not form functional channels on its own, it can form functional heterotetrameric channels with KCNB1 and KCNB2. Each regulatory subunit has unique regulatory properties that can lead to extensive inhibition, significant changes in kinetics, and/or substantial shifts in the voltage dependencies of the inactivation process. |
| Protein Name | Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns1Delayed-Rectifier K(+ Channel Alpha Subunit 1Delayed-Rectifier Potassium Channel Subunit Kv9.1Hkv9.1Potassium Voltage-Gated Channel Modifier Subfamily S Member 1 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMay Not Reach The Plasma Membrane But Remain In An Intracellular Compartment In The Absence Of Kcnb1 Or Kcnb2 |
| Alternative Antibody Names | Anti-Delayed-Rectifier Potassium Channel Regulatory Subunit Kcns1 antibodyAnti-Delayed-Rectifier K(+ Channel Alpha Subunit 1 antibodyAnti-Delayed-Rectifier Potassium Channel Subunit Kv9.1 antibodyAnti-Hkv9.1 antibodyAnti-Potassium Voltage-Gated Channel Modifier Subfamily S Member 1 antibodyAnti-KCNS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
