• Western blot analysis of extracts of NCI-H460 cells, using KCNN3 antibody (STJ27878) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-KCNN3 antibody (237-426) (STJ27878)

SKU:
STJ27878

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KCNN3 (237-426) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNN3
Gene ID: 3782
Uniprot ID: KCNN3_HUMAN
Immunogen Region: 237-426
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-426 of human KCNN3 (NP_740752.1).
Immunogen Sequence: VARKLELTKAEKHVHNFMMD TQLTKRIKNAAANVLRETWL IYKHTKLLKKIDHAKVRKHQ RKFLQAIHQLRSVKMEQRKL SDQANTLVDLSKMQNVMYDL ITELNDRSEDLEKQIGSLES KLEHLTASFNSLPLLIADTL RQQQQQLLSAIIEARGVSVA VGTTHTPISDSPIGVSSTSF PTPYTSSSSC
Function Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization.
Protein Name Small Conductance Calcium-Activated Potassium Channel Protein 3
Sk3
Skca 3
Skca3
Kca2.3
Database Links Reactome: R-HSA-1296052
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Small Conductance Calcium-Activated Potassium Channel Protein 3 antibody
Anti-Sk3 antibody
Anti-Skca 3 antibody
Anti-Skca3 antibody
Anti-Kca2.3 antibody
Anti-KCNN3 antibody
Anti-K3 antibody

Information sourced from Uniprot.org

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