| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNK3 (250-394) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNK3 |
| Gene ID: |
3777 |
| Uniprot ID: |
KCNK3_HUMAN |
| Immunogen Region: |
250-394 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 250-394 of human KCNK3 (NP_002237.1). |
| Immunogen Sequence: |
NAEDEKRDAEHRALLTRNGQ AGGGGGGGSAHTTDTASSTA AAGGGGFRNVYAEVLHFQSM CSCLWYKSREKLQYSIPMII PRDLSTSDTCVEQSHSSPGG GGRYSDTPSRRCLCSGAPRS AISSVSTGLHSLSTFRGLMK RRSSV |
| Tissue Specificity | Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon. |
| Function | pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward. |
| Protein Name | Potassium Channel Subfamily K Member 3Acid-Sensitive Potassium Channel Protein Task-1Twik-Related Acid-Sensitive K(+ Channel 1Two Pore Potassium Channel Kt3.1Two Pore K(+ Channel Kt3.1 |
| Database Links | Reactome: R-HSA-1299316Reactome: R-HSA-5576886 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily K Member 3 antibodyAnti-Acid-Sensitive Potassium Channel Protein Task-1 antibodyAnti-Twik-Related Acid-Sensitive K(+ Channel 1 antibodyAnti-Two Pore Potassium Channel Kt3.1 antibodyAnti-Two Pore K(+ Channel Kt3.1 antibodyAnti-KCNK3 antibodyAnti-TASK antibodyAnti-TASK1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
