Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-KCNK10 (384-543) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KCNK10 |
Gene ID: |
54207 |
Uniprot ID: |
KCNKA_HUMAN |
Immunogen Region: |
384-543 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 384-543 of human KCNK10 (NP_612191.1). |
Immunogen Sequence: |
RLGLDQRAHSLDMLSPEKRS VFAALDTGRFKASSQESINN RPNNLRLKGPEQLNKHGQGA SEDNIINKFGSTSRLTKRKN KDLKKTLPEDVQKIYKTFRN YSLDEEKKEEETEKMCNSDN SSTAMLTDCIQQHAELENGM IPTDTKDREPENNSLLEDRN |
Tissue Specificity | Abundantly expressed in pancreas and kidney and to a lower level in brain, testis, colon, and small intestine. Isoform b is strongly expressed in kidney (primarily in the proximal tubule) and pancreas, whereas isoform c is abundantly expressed in brain. |
Function | Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids. |
Protein Name | Potassium Channel Subfamily K Member 10Outward Rectifying Potassium Channel Protein Trek-2Trek-2 K(+ Channel Subunit |
Database Links | Reactome: R-HSA-1299503Reactome: R-HSA-5576886 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Potassium Channel Subfamily K Member 10 antibodyAnti-Outward Rectifying Potassium Channel Protein Trek-2 antibodyAnti-Trek-2 K(+ Channel Subunit antibodyAnti-KCNK10 antibodyAnti-TREK2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance