Post Translational Modifications | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. |
Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells. |
Protein Name | Inter-Alpha-Trypsin Inhibitor Heavy Chain H1Iti Heavy Chain H1Iti-Hc1Inter-Alpha-Inhibitor Heavy Chain 1Inter-Alpha-Trypsin Inhibitor Complex Component IiiSerum-Derived Hyaluronan-Associated ProteinShap |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Inter-Alpha-Trypsin Inhibitor Heavy Chain H1 antibodyAnti-Iti Heavy Chain H1 antibodyAnti-Iti-Hc1 antibodyAnti-Inter-Alpha-Inhibitor Heavy Chain 1 antibodyAnti-Inter-Alpha-Trypsin Inhibitor Complex Component Iii antibodyAnti-Serum-Derived Hyaluronan-Associated Protein antibodyAnti-Shap antibodyAnti-ITIH1 antibodyAnti-IGHEP1 antibody |
Information sourced from Uniprot.org