Anti-IRAG2 antibody (STJA0008516)

SKU:
STJA0008516
£48.00 - £252.00
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Inositol 1, 4, 5-triphosphate receptor associated 2 is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IRAG2
Gene ID: 4033
Uniprot ID: IRAG2_HUMAN
Specificity: This antibody detects endogenous levels of LRMP at Human
Immunogen: Synthesized peptide derived from human LRMP
Post Translational Modifications The removal of the C-terminal lumenal domain occurs by proteolytic processing.
Function Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules.this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules. Plays a role in the regulation of cellular excitability by regulating the hyperpolarization-activated cyclic nucleotide-gated HCN4 channel activity.
Protein Name Inositol 1 -4 -5-Triphosphate Receptor Associated 2
Lymphoid-Restricted Membrane Protein
Protein Jaw1 Cleaved Into - Processed Inositol 1 -4 -5-Triphosphate Receptor Associated 2
Database Links Reactome: R-HSA-6798695
Cellular Localisation Processed Inositol 1
4
5-Triphosphate Receptor Associated 2: Cytoplasm
Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Nucleus Envelope
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle Pole
Chromosome
Colocalized With Itpr3 On The Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Inositol 1 -4 -5-Triphosphate Receptor Associated 2 antibody
Anti-Lymphoid-Restricted Membrane Protein antibody
Anti-Protein Jaw1 Cleaved Into - Processed Inositol 1 -4 -5-Triphosphate Receptor Associated 2 antibody
Anti-IRAG2 antibody
Anti-JAW1 antibody
Anti-LRMP antibody

Information sourced from Uniprot.org

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