| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Integrator Complex Subunit 11 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S4922RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:2000-1:7000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Function | Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. |
| Protein Name | Integrator Complex Subunit 11Int11Cleavage And Polyadenylation-Specific Factor 3-Like ProteinCpsf3-Like ProteinProtein Related To Cpsf Subunits Of 68 KdaRc-68 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Integrator Complex Subunit 11 antibodyAnti-Int11 antibodyAnti-Cleavage And Polyadenylation-Specific Factor 3-Like Protein antibodyAnti-Cpsf3-Like Protein antibodyAnti-Protein Related To Cpsf Subunits Of 68 Kda antibodyAnti-Rc-68 antibodyAnti-INTS11 antibodyAnti-CPSF3L antibodyAnti-RC68 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
