• Western blot analysis of extracts of various cell lines, using INHBC antibody (STJ29697) at 1:1000 dilution. _Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. _Lysates/proteins: 25 Mu g per lane. _Blocking buffer: 3% nonfat dry milk in TBST. _Detection: ECL Enhanced Kit. _Exposure time: 90s.

Anti-INHBC antibody (103-352) (STJ29697)

SKU:
STJ29697

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-INHBC (103-352) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: INHBC
Gene ID: 3626
Uniprot ID: INHBC_HUMAN
Immunogen Region: 103-352
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 103-352 of human INHBC (NP_005529.1).
Immunogen Sequence: ETGLSTINQTRLDFHFSSDR TAGDREVQQASLMFFVQLPS NTTWTLKVRVLVLGPHNTNL TLATQYLLEVDASGWHQLPL GPEAQAACSQGHLTLELVLE GQVAQSSVILGGAAHRPFVA ARVRVGGKHQIHRRGIDCQG GSRMCCRQEFFVDFREIGWH DWIIQPEGYAMNFCIGQCPL HIAGMPGIAASFHTAVLNLL KANTAAGTTGGGSCCVPTAR RPLSLLYYDRDSNIVKTDI
Tissue Specificity Expressed in benign prostatic hyperplasia.
Function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Protein Name Inhibin Beta C Chain
Activin Beta-C Chain
Database Links Reactome: R-HSA-209822
Cellular Localisation Secreted
Alternative Antibody Names Anti-Inhibin Beta C Chain antibody
Anti-Activin Beta-C Chain antibody
Anti-INHBC antibody

Information sourced from Uniprot.org

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