• Western blot analysis of various lysates using IL1RAPL1 Rabbit polyclonal antibody (STJ116202) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-IL1RAPL1 antibody (130-210) (STJ116202)

SKU:
STJ116202

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-IL1RAPL1 (130-210) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IL1RAPL1
Gene ID: 11141
Uniprot ID: IRPL1_HUMAN
Immunogen Region: 130-210
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human IL1RAPL1 (NP_055086.1).
Immunogen Sequence: SISLTVGENDTGLCYNSKMK YFEKAELSKSKEISCRDIED FLLPTREPEILWYKECRTKT WRPSIVFKRDTLLIREVRED D
Tissue Specificity Detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. Detected at very low levels in tonsil, prostate, testis, small intestine, placenta, colon and fetal liver.
Function May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth. During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
Protein Name Interleukin-1 Receptor Accessory Protein-Like 1
Il-1-Rapl-1
Il-1rapl-1
Il1rapl-1
Oligophrenin-4
Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2
Tigirr-2
X-Linked Interleukin-1 Receptor Accessory Protein-Like 1
Database Links Reactome: R-HSA-388844
Reactome: R-HSA-9007892
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasm
Cell Projection
Axon
Dendrite
May Localize To The Cell Body And Growth Cones Of Dendrite-Like Processes
Alternative Antibody Names Anti-Interleukin-1 Receptor Accessory Protein-Like 1 antibody
Anti-Il-1-Rapl-1 antibody
Anti-Il-1rapl-1 antibody
Anti-Il1rapl-1 antibody
Anti-Oligophrenin-4 antibody
Anti-Three Immunoglobulin Domain-Containing Il-1 Receptor-Related 2 antibody
Anti-Tigirr-2 antibody
Anti-X-Linked Interleukin-1 Receptor Accessory Protein-Like 1 antibody
Anti-IL1RAPL1 antibody
Anti-OPHN4 antibody

Information sourced from Uniprot.org

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