Host: |
Mouse |
Applications: |
FC |
Reactivity: |
Human/Cow/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD54 is suitable for use in Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
MEM-111 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2a |
Formulation: |
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Immunogen: |
Raji human Burkitt's lymphoma cell line |
Background | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B-and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance