| Tissue Specificity | Expressed in bone (at protein level). Expressed in trophoblast cells of placenta (at protein level). Expressed in brain. |
| Post Translational Modifications | N-glycosylated.glycans consist of sialylated and core-fucosylated bi-, tri- and tetraantennary chains. O-glycosylated at eight sites.mucin-type glycans contain Gal, GlcNAc, GalNAc and terminal NeuAc. |
| Function | Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes adhesion and migration of various cells via the alpha-V/beta-3 integrin receptor (ITGAV:ITGB3). |
| Protein Name | Integrin-Binding SialoproteinBone Sialoprotein 2Bone Sialoprotein IiBsp IiCell-Binding Sialoprotein |
| Database Links | Reactome: R-HSA-216083Reactome: R-HSA-3000178 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Integrin-Binding Sialoprotein antibodyAnti-Bone Sialoprotein 2 antibodyAnti-Bone Sialoprotein Ii antibodyAnti-Bsp Ii antibodyAnti-Cell-Binding Sialoprotein antibodyAnti-IBSP antibodyAnti-BNSP antibody |
Information sourced from Uniprot.org
