• Western blot analysis of extracts of various cell lines, using HVCN1 antibody (STJ111499) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.
  • Western blot analysis of extracts of various cell lines, using HVCN1 antibody (STJ111499) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.

Anti-HVCN1 antibody (1-100) (STJ111499)

SKU:
STJ111499

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-HVCN1 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: HVCN1
Gene ID: 84329
Uniprot ID: HVCN1_HUMAN
Immunogen Region: 1-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human HVCN1 (NP_115745.2).
Immunogen Sequence: MATWDEKAVTRRAKVAPAER MSKFLRHFTVVGDDYHAWNI NYKKWENEEEEEEEEQPPPT PVSGEEGRAAAPDVAPAPGP APRAPLDFRGMLRKLFSSHR
Tissue Specificity Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen.
Post Translational Modifications Phosphorylation may enhance channel gating.
Function Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis.
Protein Name Voltage-Gated Hydrogen Channel 1
Hydrogen Voltage-Gated Channel 1
Hv1
Voltage Sensor Domain-Only Protein
Database Links Reactome: R-HSA-1222556
Reactome: R-HSA-1300642
Reactome: R-HSA-6798695
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Cell Membrane
Detected Mainly At Intracellular Membranes Upon Overexpression In Hela Cells
But Not In Other Cell Types
Alternative Antibody Names Anti-Voltage-Gated Hydrogen Channel 1 antibody
Anti-Hydrogen Voltage-Gated Channel 1 antibody
Anti-Hv1 antibody
Anti-Voltage Sensor Domain-Only Protein antibody
Anti-HVCN1 antibody
Anti-VSOP antibody
Anti-UNQ578 antibody
Anti-PRO1140 antibody

Information sourced from Uniprot.org

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