• Human Kaposi’s sarcoma stained with anti-HHV-8 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of sarcoma cells.

Anti-HHV-8 antibody [ZR106] (STJ180387)

SKU:
STJ180387

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Host: Rabbit
Applications: IHC-P
Reactivity: HHV8
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-HHV-8 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZR106
Conjugation: Unconjugated
Isotype: Rabbit IgG
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Specificity: Positive control: Kaposi's sarcoma
Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
Background HHV8 encodes a latent nuclear antigen (LNA) , which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; Kaposi s sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman s disease. HHV8 is the likely etiological agent of Kaposi s sarcoma.

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance