| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | HHIP |
| Gene ID: | 64399 |
| Uniprot ID: | HHIP_HUMAN |
| Immunogen Region: | 400-700 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human HHIP (NP_071920.1). |
| Immunogen Sequence: | DMCNVPYSIPRSNPHFNSTN QPPEVFAHGLHDPGRCAVDR HPTDININLTILCSDSNGKN RSSARILQIIKGKDYESEPS LLEFKPFSNGPLVGGFVYRG CQSERLYGSYVFGDRNGNFL TLQQSPVTKQWQEKPLCLGT SGSCRGYFSGHILGFGEDEL GEVYILSSSKSMTQTHNGKL YKIVDPKRPLMPEECRATVQ PAQTLTSECSRLCRNGYCTP TGKCCCSPGWEGDFCRTAK |
| Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. |
| Function | Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. |
| Protein Name | Hedgehog-Interacting ProteinHhipHip |
| Database Links | Reactome: R-HSA-5632681 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinSecretedThe Last 22 C-Terminal Amino Acids May Participate In Cell Membrane AttachmentIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Hedgehog-Interacting Protein antibodyAnti-Hhip antibodyAnti-Hip antibodyAnti-HHIP antibodyAnti-HIP antibodyAnti-UNQ5825 antibodyAnti-PRO19644 antibody |
Information sourced from Uniprot.org