| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-HHAT (1-100) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
HHAT |
| Gene ID: |
55733 |
| Uniprot ID: |
HHAT_HUMAN |
| Immunogen Region: |
1-100 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HHAT (NP_060664.2). |
| Immunogen Sequence: |
MLPRWELALYLLASLGFHFY SFYEVYKVSREHEEELDQEF ELETDTLFGGLKKDATDFEW SFWMEWGKQWLVWLLLGHMV VSQMATLLARKHRPWILMLY |
| Tissue Specificity | Widely expressed. Expressed in fetal ovary and testis, with high levels of expression observed in Sertoli cells. |
| Function | Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH.which is required for SHH signaling. It also catalyzes N-terminal palmitoylation of DHH. Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs. It is an essential factor for proper embryonic development and testicular organogenesis. |
| Protein Name | Protein-Cysteine N-Palmitoyltransferase HhatHedgehog AcyltransferaseMelanoma Antigen Recognized By T-Cells 2Mart-2Skinny Hedgehog Protein 1 |
| Database Links | Reactome: R-HSA-5358346Reactome: R-HSA-5658034 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCo-Localizes With Shh In The Er And Golgi Membrane |
| Alternative Antibody Names | Anti-Protein-Cysteine N-Palmitoyltransferase Hhat antibodyAnti-Hedgehog Acyltransferase antibodyAnti-Melanoma Antigen Recognized By T-Cells 2 antibodyAnti-Mart-2 antibodyAnti-Skinny Hedgehog Protein 1 antibodyAnti-HHAT antibodyAnti-MART2 antibodyAnti-SKI1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
