• Immunofluorescence analysis of mouse brain using mGluR2 Rabbit monoclonal antibody (STJ11101921) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of rat brain using mGluR2 Rabbit monoclonal antibody (STJ11101921) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using mGluR2 Rabbit monoclonal antibody (STJ11101921) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3min.

Anti-GRM2 antibody (773-872) [S1MR] (STJ11101921)

SKU:
STJ11101921

£212.50 - £501.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-mGluR2 (773-872) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRM2
Gene ID: 2912
Uniprot ID: GRM2_HUMAN
Immunogen Region: 773-872
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 773-872 of human mGluR2 (Q14416).
Immunogen Sequence: WLAFLPIFYVTSSDYRVQTT TMCVSVSLSGSVVLGCLFAP KLHIILFQPQKNVVSHRAPT SRFGSAAARASSSLGQGSGS QFVPTVCNGREVVDSTTSSL
Tissue Specificity Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Protein Name Metabotropic Glutamate Receptor 2
Mglur2
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-420499
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Synapse
Cell Projection
Dendrite
Alternative Antibody Names Anti-Metabotropic Glutamate Receptor 2 antibody
Anti-Mglur2 antibody
Anti-GRM2 antibody
Anti-GPRC1B antibody
Anti-MGLUR2 antibody

Information sourced from Uniprot.org

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