• Western blot analysis of extracts of various cell lines, using GRK3 antibody (STJ11103652) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
  • Western blot analysis of extracts of various cell lines, using GRK3 antibody (STJ11103652) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-GRK3 antibody (589-688) [S2MR] (STJ11103652)

SKU:
STJ11103652

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-GRK3 (589-688) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GRK3
Gene ID: 157
Uniprot ID: ARBK2_HUMAN
Immunogen Region: 589-688
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 589-688 of human GRK3 (P35626).
Immunogen Sequence: EWRGEGESRQNLLTMEQILS VEETQIKDKKCILFRIKGGK QFVLQCESDPEFVQWKKELN ETFKEAQRLLRRAPKFLNKP RSGTVELPKPSLCHRNSNGL
Post Translational Modifications Ubiquitinated.
Function Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Protein Name Beta-Adrenergic Receptor Kinase 2
Beta-Ark-2
G-Protein-Coupled Receptor Kinase 3
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-8856825
Cellular Localisation Postsynapse
Presynapse
Alternative Antibody Names Anti-Beta-Adrenergic Receptor Kinase 2 antibody
Anti-Beta-Ark-2 antibody
Anti-G-Protein-Coupled Receptor Kinase 3 antibody
Anti-GRK3 antibody
Anti-ADRBK2 antibody
Anti-BARK2 antibody

Information sourced from Uniprot.org

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