| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GPX7 |
| Gene ID: | 2882 |
| Uniprot ID: | GPX7_HUMAN |
| Immunogen Region: | 20-187 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-187 of human GPX7 (NP_056511.2). |
| Immunogen Sequence: | QQEQDFYDFKAVNIRGKLVS LEKYRGSVSLVVNVASECGF TDQHYRALQQLQRDLGPHHF NVLAFPCNQFGQQEPDSNKE IESFARRTYSVSFPMFSKIA VTGTGAHPAFKYLAQTSGKE PTWNFWKYLVAPDGKVVGAW DPTVSVEEVRPQITALVRKL ILLKREDL |
| Tissue Specificity | Expressed in esophageal epithelial cells.expression is up-regulated after exposure to acidic bile acids. |
| Function | It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxygen species (ROS) and protects against oxidative DNA damage and double-strand breaks. |
| Protein Name | Glutathione Peroxidase 7Gpx-7Gshpx-7Cl683 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Glutathione Peroxidase 7 antibodyAnti-Gpx-7 antibodyAnti-Gshpx-7 antibodyAnti-Cl683 antibodyAnti-GPX7 antibodyAnti-GPX6 antibodyAnti-UNQ469 antibodyAnti-PRO828 antibody |
Information sourced from Uniprot.org