Anti-GPBAR1 antibody (11-60 aa) (STJ96001)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human GPBAR at the amino acid range 11-60
General Information
| Short Description | Rabbit polyclonal anti-G-protein coupled bile acid receptor 1 (11-60 aa) for use in WB, ELISA and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPBAR1 |
| Gene ID | 151306 |
| Uniprot ID | GPBAR_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human GPBAR at the amino acid range 11-60 |
| Immunogen Region | 11-60 aa |
| Specificity | TGR5 Polyclonal Antibody detects endogenous levels of TGR5 protein. |
Additional Info
| Function | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. |
| Protein Name | G-Protein Coupled Bile Acid Receptor 1G-Protein Coupled Receptor Gpcr19Hgpcr19Membrane-Type Receptor For Bile AcidsM-BarHbg37Bg37 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418555 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G-Protein Coupled Bile Acid Receptor 1 antibodyAnti-G-Protein Coupled Receptor Gpcr19 antibodyAnti-Hgpcr19 antibodyAnti-Membrane-Type Receptor For Bile Acids antibodyAnti-M-Bar antibodyAnti-Hbg37 antibodyAnti-Bg37 antibodyAnti-GPBAR1 antibodyAnti-TGR5 antibody |
Information sourced from Uniprot.org