| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-GLYAT (1-163) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
GLYAT |
| Gene ID: |
10249 |
| Uniprot ID: |
GLYAT_HUMAN |
| Immunogen Region: |
1-163 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-163 of human GLYAT (NP_005829.3). |
| Immunogen Sequence: |
MMLPLQGAQMLQMLEKSLRK SLPASLKVYGTVFHINHGNP FNLKAVVDKWPDFNTVVVCP QEQDMTDDLDHYTNTYQIYS KDPQNCQEFLGSPELINWKQ HLQIQSSQPSLNEAIQNLAA IKSFKVKQTQRILYMAAETA KELTPFLLKSKILSPNGGKP KAM |
| Tissue Specificity | Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. |
| Function | Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. |
| Protein Name | Glycine N-AcyltransferaseAcyl-Coa -Glycine N-AcyltransferaseAacAralkyl Acyl-Coa N-AcyltransferaseAralkyl Acyl-Coa -Amino Acid N-AcyltransferaseBenzoyl-Coenzyme A -Glycine N-AcyltransferaseGlycine N-BenzoyltransferaseHrp-1(Clp |
| Database Links | Reactome: R-HSA-177128Reactome: R-HSA-177135Reactome: R-HSA-9749641 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Glycine N-Acyltransferase antibodyAnti-Acyl-Coa -Glycine N-Acyltransferase antibodyAnti-Aac antibodyAnti-Aralkyl Acyl-Coa N-Acyltransferase antibodyAnti-Aralkyl Acyl-Coa -Amino Acid N-Acyltransferase antibodyAnti-Benzoyl-Coenzyme A -Glycine N-Acyltransferase antibodyAnti-Glycine N-Benzoyltransferase antibodyAnti-Hrp-1(Clp antibodyAnti-GLYAT antibodyAnti-ACGNAT antibodyAnti-CAT antibodyAnti-GAT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
