| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GLUD2 |
| Gene ID: | 2747 |
| Uniprot ID: | DHE4_HUMAN |
| Immunogen Region: | 319-558 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 319-558 of human GLUD2 (NP_036216.2). |
| Immunogen Sequence: | YLHRFGAKCIAVGESDGSIW NPDGIDPKELEDFKLQHGSI LGFPKAKPYEGSILEVDCDI LIPAATEKQLTKSNAPRVKA KIIAEGANGPTTPEADKIFL ERNILVIPDLYLNAGGVTVS YFEWLKNLNHVSYGRLTFKY ERDSNYHLLLSVQESLERKF GKHGGTIPIVPTAEFQDSIS GASEKDIVHSALAYTMERSA RQIMHTAMKYNLGLDLRTAA YVNAIEKVFKVYSEAGVTF |
| Tissue Specificity | Expressed in retina, testis and, at a lower level, brain. |
| Post Translational Modifications | Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer. |
| Function | Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. |
| Protein Name | Glutamate Dehydrogenase 2 - MitochondrialGdh 2 |
| Database Links | Reactome: R-HSA-2151201Reactome: R-HSA-8964539 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Glutamate Dehydrogenase 2 - Mitochondrial antibodyAnti-Gdh 2 antibodyAnti-GLUD2 antibodyAnti-GLUDP1 antibody |
Information sourced from Uniprot.org