• Western blot analysis of extracts of various cell lines, using GLP1R antibody (STJ111286) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Immunofluorescence analysis of L929 cells using GLP1R antibody (STJ111286) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunofluorescence analysis of L929 cells using GLP1R antibody (STJ111286) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Western blot analysis of extracts of various cell lines, using GLP1R antibody (STJ111286) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-GLP1R antibody (1-140) (STJ111286)

SKU:
STJ111286

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IF
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GLP1R (1-140) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GLP1R
Gene ID: 2740
Uniprot ID: GLP1R_HUMAN
Immunogen Region: 1-140
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human GLP1R (NP_002053.3).
Immunogen Sequence: MAGAPGPLRLALLLLGMVGR AGPRPQGATVSLWETVQKWR EYRRQCQRSLTEDPPPATDL FCNRTFDEYACWPDGEPGSF VNVSCPWYLPWASSVPQGHV YRFCTAEGLWLQKDNSSLPW RDLSECEESKRGERSSPEEQ
Post Translational Modifications N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
Function G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.
Protein Name Glucagon-Like Peptide 1 Receptor
Glp-1 Receptor
Glp-1-R
Glp-1r
Database Links Reactome: R-HSA-381676
Reactome: R-HSA-418555
Reactome: R-HSA-420092
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Glucagon-Like Peptide 1 Receptor antibody
Anti-Glp-1 Receptor antibody
Anti-Glp-1-R antibody
Anti-Glp-1r antibody
Anti-GLP1R antibody

Information sourced from Uniprot.org

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