Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-GJC2 (400-500) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GJC2 |
Gene ID: |
57165 |
Uniprot ID: |
CXG2_HUMAN |
Immunogen Region: |
400-500 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human GJC2 (Q5T442). |
Immunogen Sequence: |
AGTVGEQGRPGTHERPGAKP RAGSEKGSASSRDGKTTVWI |
Tissue Specificity | Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. |
Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. |
Protein Name | Gap Junction Gamma-2 ProteinConnexin-46.6Cx46.6Connexin-47Cx47Gap Junction Alpha-12 Protein |
Database Links | Reactome: R-HSA-190861 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap Junction |
Alternative Antibody Names | Anti-Gap Junction Gamma-2 Protein antibodyAnti-Connexin-46.6 antibodyAnti-Cx46.6 antibodyAnti-Connexin-47 antibodyAnti-Cx47 antibodyAnti-Gap Junction Alpha-12 Protein antibodyAnti-GJC2 antibodyAnti-GJA12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance