• Western blot analysis of lysates from mouse brain, using GJC2 Rabbit polyclonal antibody (STJ23796) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-GJC2 antibody (400-500) (STJ23796)

SKU:
STJ23796

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GJC2 (400-500) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GJC2
Gene ID: 57165
Uniprot ID: CXG2_HUMAN
Immunogen Region: 400-500
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human GJC2 (Q5T442).
Immunogen Sequence: AGTVGEQGRPGTHERPGAKP RAGSEKGSASSRDGKTTVWI
Tissue Specificity Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles.
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems.
Protein Name Gap Junction Gamma-2 Protein
Connexin-46.6
Cx46.6
Connexin-47
Cx47
Gap Junction Alpha-12 Protein
Database Links Reactome: R-HSA-190861
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Junction
Gap Junction
Alternative Antibody Names Anti-Gap Junction Gamma-2 Protein antibody
Anti-Connexin-46.6 antibody
Anti-Cx46.6 antibody
Anti-Connexin-47 antibody
Anti-Cx47 antibody
Anti-Gap Junction Alpha-12 Protein antibody
Anti-GJC2 antibody
Anti-GJA12 antibody

Information sourced from Uniprot.org

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