| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GJC2 |
| Gene ID: | 57165 |
| Uniprot ID: | CXG2_HUMAN |
| Immunogen Region: | 400-500 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human GJC2 (Q5T442). |
| Immunogen Sequence: | AGTVGEQGRPGTHERPGAKP RAGSEKGSASSRDGKTTVWI |
| Tissue Specificity | Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. |
| Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. |
| Protein Name | Gap Junction Gamma-2 ProteinConnexin-46.6Cx46.6Connexin-47Cx47Gap Junction Alpha-12 Protein |
| Database Links | Reactome: R-HSA-190861 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap Junction |
| Alternative Antibody Names | Anti-Gap Junction Gamma-2 Protein antibodyAnti-Connexin-46.6 antibodyAnti-Cx46.6 antibodyAnti-Connexin-47 antibodyAnti-Cx47 antibodyAnti-Gap Junction Alpha-12 Protein antibodyAnti-GJC2 antibodyAnti-GJA12 antibody |
Information sourced from Uniprot.org