| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GJB4 |
| Gene ID: | 127534 |
| Uniprot ID: | CXB4_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human GJB4 (NP_694944.1). |
| Immunogen Sequence: | ERERKHHLKHGPNAPSLYDN LSKKRGGLWWTYLLSLIFKA AVDAGFLYIFHRLYKDYDMP RVVACSVEPCPHTVDCYISR PTEKKVFTYFMVTTAAICIL L |
| Function | Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. |
| Protein Name | Gap Junction Beta-4 ProteinConnexin-30.3Cx30.3 |
| Database Links | Reactome: R-HSA-190861 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionGap JunctionColocalizes With Gjb2 At Gap Junction Plaques In The Cochlea |
| Alternative Antibody Names | Anti-Gap Junction Beta-4 Protein antibodyAnti-Connexin-30.3 antibodyAnti-Cx30.3 antibodyAnti-GJB4 antibody |
Information sourced from Uniprot.org