Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 3 (226-275 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
GCNT3 |
Gene ID: |
9245 |
Uniprot ID: |
GCNT3_HUMAN |
Immunogen Region: |
226-275 aa |
Specificity: |
GCNT3 Polyclonal Antibody detects endogenous levels of GCNT3 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human GCNT3 at the amino acid range 226-275 |
Post Translational Modifications | N-glycosylated. |
Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
Protein Name | Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 C2gnt-Mucin TypeC2gnt-MHc2gnt-MCore 2/Core 4 Beta-1 -6-N-AcetylglucosaminyltransferaseC2/4gnt |
Database Links | Reactome: R-HSA-913709 |
Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Beta-1 -3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1 -6-N-Acetylglucosaminyltransferase 3 antibodyAnti-C2gnt-Mucin Type antibodyAnti-C2gnt-M antibodyAnti-Hc2gnt-M antibodyAnti-Core 2/Core 4 Beta-1 -6-N-Acetylglucosaminyltransferase antibodyAnti-C2/4gnt antibodyAnti-GCNT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance