| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FUT1 (130-310) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FUT1 |
| Gene ID: |
2523 |
| Uniprot ID: |
FUT1_HUMAN |
| Immunogen Region: |
130-310 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 130-310 of human FUT1 (NP_000139.1). |
| Immunogen Sequence: |
VLAPEVDSRTPWRELQLHDW MSEEYADLRDPFLKLSGFPC SWTFFHHLREQIRREFTLHD HLREEAQSVLGQLRLGRTGD RPRTFVGVHVRRGDYLQVMP QRWKGVVGDSAYLRQAMDWF RARHEAPVFVVTSNGMEWCK ENIDTSQGDVTFAGDGQEAT PWKDFALLTQCNHTIMTIGT F |
| Function | Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens. H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis. Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a. |
| Protein Name | Galactoside Alpha-(1 -2-Fucosyltransferase 1Alpha(1 -2ft 1Blood Group H Alpha 2-FucosyltransferaseFucosyltransferase 1Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 |
| Database Links | Reactome: R-HSA-9033807 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinMembrane-Bound Form In Trans Cisternae Of Golgi |
| Alternative Antibody Names | Anti-Galactoside Alpha-(1 -2-Fucosyltransferase 1 antibodyAnti-Alpha(1 -2ft 1 antibodyAnti-Blood Group H Alpha 2-Fucosyltransferase antibodyAnti-Fucosyltransferase 1 antibodyAnti-Gdp-L-Fucose -Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1 antibodyAnti-Type 1 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 antibodyAnti-Type 2 Galactoside Alpha-(1 -2-Fucosyltransferase Fut1 antibodyAnti-FUT1 antibodyAnti-H antibodyAnti-HSC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
