| Short Description : | Rabbit monoclonal FUBP1 (545-644) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S6MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FUBP1 |
| Gene ID: | 8880 |
| Uniprot ID: | FUBP1_HUMAN |
| Immunogen Region: | 545-644 |
| Immunogen Sequence: | YQQQAQPPPAAPAGAPTTTQ TNGQGDQQNPAPAGQVDYTK AWEEYYKKMGQAVPAPTGAP PGGQPDYSAAWAEYYRQQAA YYAQTSPQGMPQHPPAPQGQ |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 545-644 of human FUBP1 (Q96AE4). |
| Post Translational Modifications | Ubiquitinated. This targets the protein for proteasome-mediated degradation. |
| Function | Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription. |
| Protein Name | Far Upstream Element-Binding Protein 1FbpFuse-Binding Protein 1Dna Helicase VHdh V |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Far Upstream Element-Binding Protein 1 antibodyAnti-Fbp antibodyAnti-Fuse-Binding Protein 1 antibodyAnti-Dna Helicase V antibodyAnti-Hdh V antibodyAnti-FUBP1 antibody |
Information sourced from Uniprot.org
