| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FSHB (19-129) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FSHB |
| Gene ID: |
2488 |
| Uniprot ID: |
FSHB_HUMAN |
| Immunogen Region: |
19-129 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 19-129 of human FSHB (NP_000501.1). |
| Immunogen Sequence: |
NSCELTNITIAIEKEECRFC ISINTTWCAGYCYTRDLVYK DPARPKIQKTCTFKELVYET VRVPGCAHHADSLYTYPVAT QCHCGKCDSDSTDCTVRGLG PSYCSFGEMKE |
| Function | Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. |
| Protein Name | Follitropin Subunit BetaFollicle-Stimulating Hormone Beta SubunitFsh-BFsh-BetaFollitropin Beta Chain |
| Database Links | Reactome: R-HSA-209822Reactome: R-HSA-375281Reactome: R-HSA-418555 |
| Cellular Localisation | SecretedEfficient Secretion Requires Dimerization With Cga |
| Alternative Antibody Names | Anti-Follitropin Subunit Beta antibodyAnti-Follicle-Stimulating Hormone Beta Subunit antibodyAnti-Fsh-B antibodyAnti-Fsh-Beta antibodyAnti-Follitropin Beta Chain antibodyAnti-FSHB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
