• Western blot analysis of various lysates using FSHB Rabbit polyclonal antibody (STJ116743) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FSHB antibody (19-129) (STJ116743)

SKU:
STJ116743

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FSHB (19-129) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FSHB
Gene ID: 2488
Uniprot ID: FSHB_HUMAN
Immunogen Region: 19-129
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-129 of human FSHB (NP_000501.1).
Immunogen Sequence: NSCELTNITIAIEKEECRFC ISINTTWCAGYCYTRDLVYK DPARPKIQKTCTFKELVYET VRVPGCAHHADSLYTYPVAT QCHCGKCDSDSTDCTVRGLG PSYCSFGEMKE
Function Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
Protein Name Follitropin Subunit Beta
Follicle-Stimulating Hormone Beta Subunit
Fsh-B
Fsh-Beta
Follitropin Beta Chain
Database Links Reactome: R-HSA-209822
Reactome: R-HSA-375281
Reactome: R-HSA-418555
Cellular Localisation Secreted
Efficient Secretion Requires Dimerization With Cga
Alternative Antibody Names Anti-Follitropin Subunit Beta antibody
Anti-Follicle-Stimulating Hormone Beta Subunit antibody
Anti-Fsh-B antibody
Anti-Fsh-Beta antibody
Anti-Follitropin Beta Chain antibody
Anti-FSHB antibody

Information sourced from Uniprot.org

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