• Western blot analysis of extracts of various cell lines, using FOXP2 antibody (STJ27644) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-FOXP2 antibody (590-715) (STJ27644)

SKU:
STJ27644

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FOXP2 (590-715) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FOXP2
Gene ID: 93986
Uniprot ID: FOXP2_HUMAN
Immunogen Region: 590-715
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 590-715 of human FOXP2 (NP_055306.1).
Immunogen Sequence: GSPTLVKNIPTSLGYGAALN ASLQAALAESSLPLLSNPGL INNASSGLLQAVHEDLNGSL DHIDSNGNSSPGCSPQPHIH SIHVKEEPVIAEDEDCPMSL VTTANHSPELEDDREIEEEP LSEDLE
Tissue Specificity Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung.
Function Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Protein Name Forkhead Box Protein P2
Cag Repeat Protein 44
Trinucleotide Repeat-Containing Gene 10 Protein
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Forkhead Box Protein P2 antibody
Anti-Cag Repeat Protein 44 antibody
Anti-Trinucleotide Repeat-Containing Gene 10 Protein antibody
Anti-FOXP2 antibody
Anti-CAGH44 antibody
Anti-TNRC10 antibody

Information sourced from Uniprot.org

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