Western blot analysis of various lysates using FMNL1 Rabbit polyclonal antibody (STJ114977) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-FMNL1 antibody (900-1070) (STJ114977)

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STJ114977
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FMNL1
Gene ID: 752
Uniprot ID: FMNL1_HUMAN
Immunogen Region: 900-1070
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2).
Immunogen Sequence: DLHFLDKAGSVSLDSVLADV RSLQRGLELTQREFVRQDDC MVLKEFLRANSPTMDKLLAD SKTAQEAFESVVEYFGENPK TTSPGLFFSLFSRFIKAYKK AEQEVEQWKKEAAAQEAGAD TPGKGEPPAPKSPPKARRPQ MDLISELKRRQQKEPLIYES DRDGAIEDIIT
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Post Translational Modifications Myristoylation mediates membrane localization and blebbing.
Function May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
Protein Name Formin-Like Protein 1
Cll-Associated Antigen Kw-13
Leukocyte Formin
Database Links Reactome: R-HSA-5663220
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Cellular Localisation Cytoplasm
Cell Membrane
Lipid-Anchor
Cytoplasmic Vesicle
Phagosome
Recruited To Actin-Rich Phagosomes During Phagocytosis
Translocates To The Plasma Membrane Upon Activation By Rac1
Isoform 3: Cytoplasm
Cell Cortex
Cell Projection
Bleb
Colocalized With F-Actin In Bleb Protrusions
Alternative Antibody Names Anti-Formin-Like Protein 1 antibody
Anti-Cll-Associated Antigen Kw-13 antibody
Anti-Leukocyte Formin antibody
Anti-FMNL1 antibody
Anti-C17orf1 antibody
Anti-C17orf1B antibody
Anti-FMNL antibody
Anti-FRL1 antibody

Information sourced from Uniprot.org

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