| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FGD1 (700-800) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FGD1 |
| Gene ID: |
2245 |
| Uniprot ID: |
FGD1_HUMAN |
| Immunogen Region: |
700-800 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2). |
| Immunogen Sequence: |
LLNSTNREDEDTPPNSPNVD LGKRAPTPIREKEVTMCMRC QEPFNSITKRRHHCKACGHV VCGKCSEFRARLVYDNNRSN RVCTDCYVALHGVPGSSPAC S |
| Tissue Specificity | Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver.adult heart, brain, lung, pancreas and skeletal muscle. |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 1Faciogenital Dysplasia 1 ProteinRho/Rac Guanine Nucleotide Exchange Factor Fgd1Rho/Rac GefZinc Finger Fyve Domain-Containing Protein 3 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCell ProjectionLamellipodiumRuffleCytoskeletonAssociated With Membrane Ruffles And Lamellipodia |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 1 antibodyAnti-Faciogenital Dysplasia 1 Protein antibodyAnti-Rho/Rac Guanine Nucleotide Exchange Factor Fgd1 antibodyAnti-Rho/Rac Gef antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 3 antibodyAnti-FGD1 antibodyAnti-FGDY antibodyAnti-ZFYVE3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
