| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FCN3 |
| Gene ID: |
8547 |
| Uniprot ID: |
FCN3_HUMAN |
| Immunogen Region: |
13-288 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1). |
| Immunogen Sequence: |
LLLGGPACLKTQEHPSCPGP RELEASKVVLLPSCPGAPGS PGEKGAPGPQGPPGPPGKMG PKGEPGPRNCRELLSQGATL SGWYHLCLPEGRALPVFCDM DTEGGGWLVFQRRQDGSVDF FRSWSSYRAGFGNQESEFWL GNENLHQLTLQGNWELRVEL EDFNGNRTFAHYATFRLLGE VDHYQLALGKFSEGTAGDSL SLHSGRPFTTYDADHDSSNS NCAVIVHGAWWYASCYRSN |
| Tissue Specificity | Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota. |
| Protein Name | Ficolin-3Collagen/Fibrinogen Domain-Containing Lectin 3 P35Collagen/Fibrinogen Domain-Containing Protein 3Hakata Antigen |
| Database Links | Reactome: R-HSA-166662Reactome: R-HSA-166663Reactome: R-HSA-2855086 |
| Cellular Localisation | SecretedFound In Blood PlasmaBronchusAlveolus And Bile Duct |
| Alternative Antibody Names | Anti-Ficolin-3 antibodyAnti-Collagen/Fibrinogen Domain-Containing Lectin 3 P35 antibodyAnti-Collagen/Fibrinogen Domain-Containing Protein 3 antibodyAnti-Hakata Antigen antibodyAnti-FCN3 antibodyAnti-FCNH antibodyAnti-HAKA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
