• Western blot analysis of various lysates using FCN3 Rabbit polyclonal antibody (STJ119478) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-FCN3 antibody (13-288) (STJ119478)

SKU:
STJ119478

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FCN3 (13-288) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCN3
Gene ID: 8547
Uniprot ID: FCN3_HUMAN
Immunogen Region: 13-288
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1).
Immunogen Sequence: LLLGGPACLKTQEHPSCPGP RELEASKVVLLPSCPGAPGS PGEKGAPGPQGPPGPPGKMG PKGEPGPRNCRELLSQGATL SGWYHLCLPEGRALPVFCDM DTEGGGWLVFQRRQDGSVDF FRSWSSYRAGFGNQESEFWL GNENLHQLTLQGNWELRVEL EDFNGNRTFAHYATFRLLGE VDHYQLALGKFSEGTAGDSL SLHSGRPFTTYDADHDSSNS NCAVIVHGAWWYASCYRSN
Tissue Specificity Liver and lung. In liver it is produced by bile duct epithelial cells and hepatocytes. In lung it is produced by both ciliated bronchial epithelial cells and type II alveolar epithelial cells.
Post Translational Modifications The N-terminus is blocked.
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
Protein Name Ficolin-3
Collagen/Fibrinogen Domain-Containing Lectin 3 P35
Collagen/Fibrinogen Domain-Containing Protein 3
Hakata Antigen
Database Links Reactome: R-HSA-166662
Reactome: R-HSA-166663
Reactome: R-HSA-2855086
Cellular Localisation Secreted
Found In Blood Plasma
Bronchus
Alveolus And Bile Duct
Alternative Antibody Names Anti-Ficolin-3 antibody
Anti-Collagen/Fibrinogen Domain-Containing Lectin 3 P35 antibody
Anti-Collagen/Fibrinogen Domain-Containing Protein 3 antibody
Anti-Hakata Antigen antibody
Anti-FCN3 antibody
Anti-FCNH antibody
Anti-HAKA1 antibody

Information sourced from Uniprot.org

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