| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-FAM46C (1-110) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TENT5C |
| Gene ID: |
54855 |
| Uniprot ID: |
TET5C_HUMAN |
| Immunogen Region: |
1-110 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human FAM46C (NP_060179.2). |
| Immunogen Sequence: |
MAEESSCTRDCMSFSVLNWD QVSRLHEVLTEVVPIHGRGN FPTLEITLKDIVQTVRSRLE EAGIKVHDVRLNGSAAGHVL VKDNGLGCKDLDLIFHVALP TEAEFQLVRD |
| Function | Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression. Can also elongate RNA oligos ending with uridine molecule, provided that the sequence is adenosine-rich. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein. (Microbial infection) Seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon. |
| Protein Name | Terminal Nucleotidyltransferase 5cNon-Canonical Poly(A Polymerase Fam46c |
| Cellular Localisation | NucleusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeRecruited Into The Centrosome Through Its Interaction With Plk4 |
| Alternative Antibody Names | Anti-Terminal Nucleotidyltransferase 5c antibodyAnti-Non-Canonical Poly(A Polymerase Fam46c antibodyAnti-TENT5C antibodyAnti-FAM46C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
