• Western blot analysis of extracts of various cell lines, using ETV6 antibody (STJ23583) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
  • Western blot analysis of extracts of various cell lines, using ETV6 antibody (STJ23583) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-ETV6 antibody (1-300) (STJ23583)

SKU:
STJ23583

£112.50 - £522.50
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ETV6 (1-300) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IHC-P 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ETV6
Gene ID: 2120
Uniprot ID: ETV6_HUMAN
Immunogen Region: 1-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_001978.1).
Immunogen Sequence: MSETPAQCSIKQERISYTPP ESPVPSYASSTPLHVPVPRA LRMEEDSIRLPAHLRLQPIY WSRDDVAQWLKWAENEFSLR PIDSNTFEMNGKALLLLTKE DFRYRSPHSGDVLYELLQHI LKQRKPRILFSPFFHPGNSI HTQPEVILHQNHEEDNCVQR TPRPSVDNVHHNPPTIELLH RSRSPITTNHRPSPDPEQRP LRSPLDNMIRRLSPAERAQG PRPHQENNHQESYPLSVSP
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression.
Function Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
Protein Name Transcription Factor Etv6
Ets Translocation Variant 6
Ets-Related Protein Tel1
Tel
Database Links Reactome: R-HSA-9673768
Reactome: R-HSA-9703465
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Etv6 antibody
Anti-Ets Translocation Variant 6 antibody
Anti-Ets-Related Protein Tel1 antibody
Anti-Tel antibody
Anti-ETV6 antibody
Anti-TEL antibody
Anti-TEL1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance