| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EPX |
| Gene ID: | 8288 |
| Uniprot ID: | PERE_HUMAN |
| Immunogen Region: | 400-500 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human EPX (NP_000493.1). |
| Immunogen Sequence: | TELRRLNPRWNGDKLYNEAR KIMGAMVQIITYRDFLPLVL GKARARRTLGHYRGYCSNVD PRVANVFTLAFRFGHTMLQP FMFRLDSQYRASAPNSHVPL S |
| Function | Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. |
| Protein Name | Eosinophil PeroxidaseEpo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cytoplasmic GranuleCytoplasmic Granules Of Eosinophils |
| Alternative Antibody Names | Anti-Eosinophil Peroxidase antibodyAnti-Epo Cleaved Into - Eosinophil Peroxidase Light Chain - Eosinophil Peroxidase Heavy Chain antibodyAnti-EPX antibodyAnti-EPER antibodyAnti-EPO antibodyAnti-EPP antibody |
Information sourced from Uniprot.org