| Tissue Specificity | Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells. |
| Function | Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock. |
| Protein Name | Ecto-Nox Disulfide-Thiol Exchanger 1Candidate Growth-Related And Time Keeping Constitutive Hydroquinone Nadh OxidaseCcnoxCell Proliferation-Inducing Gene 38 ProteinConstitutive Ecto-NoxCnox Includes - Hydroquinone Nadh Oxidase - Protein Disulfide-Thiol Oxidoreductase |
| Cellular Localisation | Cell MembraneSecretedExtracellular SpaceExtracellular And Plasma Membrane-Associated |
| Alternative Antibody Names | Anti-Ecto-Nox Disulfide-Thiol Exchanger 1 antibodyAnti-Candidate Growth-Related And Time Keeping Constitutive Hydroquinone Nadh Oxidase antibodyAnti-Ccnox antibodyAnti-Cell Proliferation-Inducing Gene 38 Protein antibodyAnti-Constitutive Ecto-Nox antibodyAnti-Cnox Includes - Hydroquinone Nadh Oxidase - Protein Disulfide-Thiol Oxidoreductase antibodyAnti-ENOX1 antibodyAnti-PIG38 antibody |
Information sourced from Uniprot.org
