| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | EFS |
| Gene ID: | 10278 |
| Uniprot ID: | EFS_HUMAN |
| Immunogen Region: | 60-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-190 of human EFS (NP_115835.1). |
| Immunogen Sequence: | TALRVPSSGPYDCPASFSHP LTRVAPQPPGEDDAPYDVPL TPKPPAELEPDLEWEGGREP GPPIYAAPSNLKRASALLNL YEAPEELLADGEGGGTDEGI YDVPLLGPEAPPSPEPPGAL ASHDQDTLAQL |
| Tissue Specificity | The protein has been detected in lung and placenta. |
| Post Translational Modifications | Phosphorylated on multiple tyrosine residues. Phosphorylated on tyrosines by FYN and SRC. |
| Function | Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. |
| Protein Name | Embryonal Fyn-Associated SubstrateHefsCas Scaffolding Protein Family Member 3 |
| Alternative Antibody Names | Anti-Embryonal Fyn-Associated Substrate antibodyAnti-Hefs antibodyAnti-Cas Scaffolding Protein Family Member 3 antibodyAnti-EFS antibodyAnti-CASS3 antibody |
Information sourced from Uniprot.org