Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DZIP3 (1-230) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DZIP3 |
Gene ID: |
9666 |
Uniprot ID: |
DZIP3_HUMAN |
Immunogen Region: |
1-230 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1). |
Immunogen Sequence: |
MDSLPDEFFVRHPAVEDQRK EETENKLEKSSGQLNKQEND IPTDLVPVNLLLEVKKLLNA INTLPKGVVPHIKKFLQEDF SFQTMQREVAANSQNGEEIV PALTLRFLITQLEAALRNIQ AGNYTAHQINIGYYLTLLFL YGVALTERGKKEDYTEAENK FLVMKMMIQENEICENFMSL VYFGRGLLRCAQKRYNGGLL EFHKSLQEIGDKNDHWFDID PTEDEDLPTT |
Tissue Specificity | Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas. |
Function | E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA. |
Protein Name | E3 Ubiquitin-Protein Ligase Dzip3Daz-Interacting Protein 3Ring-Type E3 Ubiquitin Transferase Dzip3Rna-Binding Ubiquitin Ligase Of 138 KdaHrul138 |
Database Links | Reactome: R-HSA-983168 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Dzip3 antibodyAnti-Daz-Interacting Protein 3 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Dzip3 antibodyAnti-Rna-Binding Ubiquitin Ligase Of 138 Kda antibodyAnti-Hrul138 antibodyAnti-DZIP3 antibodyAnti-KIAA0675 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance