• Western blot analysis of extracts of 293T cells, using DZIP3 Antibody (STJ29259) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.

Anti-DZIP3 antibody (1-230) (STJ29259)

SKU:
STJ29259

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DZIP3 (1-230) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DZIP3
Gene ID: 9666
Uniprot ID: DZIP3_HUMAN
Immunogen Region: 1-230
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1).
Immunogen Sequence: MDSLPDEFFVRHPAVEDQRK EETENKLEKSSGQLNKQEND IPTDLVPVNLLLEVKKLLNA INTLPKGVVPHIKKFLQEDF SFQTMQREVAANSQNGEEIV PALTLRFLITQLEAALRNIQ AGNYTAHQINIGYYLTLLFL YGVALTERGKKEDYTEAENK FLVMKMMIQENEICENFMSL VYFGRGLLRCAQKRYNGGLL EFHKSLQEIGDKNDHWFDID PTEDEDLPTT
Tissue Specificity Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
Function E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
Protein Name E3 Ubiquitin-Protein Ligase Dzip3
Daz-Interacting Protein 3
Ring-Type E3 Ubiquitin Transferase Dzip3
Rna-Binding Ubiquitin Ligase Of 138 Kda
Hrul138
Database Links Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Dzip3 antibody
Anti-Daz-Interacting Protein 3 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Dzip3 antibody
Anti-Rna-Binding Ubiquitin Ligase Of 138 Kda antibody
Anti-Hrul138 antibody
Anti-DZIP3 antibody
Anti-KIAA0675 antibody

Information sourced from Uniprot.org

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