• Western blot analysis of various lysates using DYNLT3 Rabbit polyclonal antibody (STJ119256) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-DYNLT3 antibody (9-99) (STJ119256)

SKU:
STJ119256

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-DYNLT3 (9-99) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DYNLT3
Gene ID: 6990
Uniprot ID: DYLT3_HUMAN
Immunogen Region: 9-99
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1).
Immunogen Sequence: DEVGFNAEEAHNIVKECVDG VLGGEDYNHNNINQWTASIV EQSLTHLVKLGKAYKYIVTC AVVQKSAYGFHTASSCFWDT TSDGTCTVRWE
Function Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis.
Protein Name Dynein Light Chain Tctex-Type 3
Protein 91/23
T-Complex-Associated Testis-Expressed 1-Like
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Chromosome
Centromere
Kinetochore
Colocalizes With Bub3 At Kinetochores Specifically During Prometaphase
Alternative Antibody Names Anti-Dynein Light Chain Tctex-Type 3 antibody
Anti-Protein 91/23 antibody
Anti-T-Complex-Associated Testis-Expressed 1-Like antibody
Anti-DYNLT3 antibody
Anti-TCTE1L antibody
Anti-TCTE1XL antibody

Information sourced from Uniprot.org

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