Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-DYNLT3 (9-99) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
DYNLT3 |
Gene ID: |
6990 |
Uniprot ID: |
DYLT3_HUMAN |
Immunogen Region: |
9-99 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1). |
Immunogen Sequence: |
DEVGFNAEEAHNIVKECVDG VLGGEDYNHNNINQWTASIV EQSLTHLVKLGKAYKYIVTC AVVQKSAYGFHTASSCFWDT TSDGTCTVRWE |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. |
Protein Name | Dynein Light Chain Tctex-Type 3Protein 91/23T-Complex-Associated Testis-Expressed 1-Like |
Cellular Localisation | NucleusCytoplasmCytoskeletonChromosomeCentromereKinetochoreColocalizes With Bub3 At Kinetochores Specifically During Prometaphase |
Alternative Antibody Names | Anti-Dynein Light Chain Tctex-Type 3 antibodyAnti-Protein 91/23 antibodyAnti-T-Complex-Associated Testis-Expressed 1-Like antibodyAnti-DYNLT3 antibodyAnti-TCTE1L antibodyAnti-TCTE1XL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance