| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DRP2 (1-240) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DRP2 |
| Gene ID: |
1821 |
| Uniprot ID: |
DRP2_HUMAN |
| Immunogen Region: |
1-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2). |
| Immunogen Sequence: |
MQPMVMQGCPYTLPRCHDWQ AADQFHHSSSLRSTCPHPQV RAAVTSPAPPQDGAGVPCLS LKLLNGSVGASGPLEPPAMN LCWNEIKKKSHNLRARLEAF SDHSGKLQLPLQEIIDWLSQ KDEELSAQLPLQGDVALVQQ EKETHAAFMEEVKSRGPYIY SVLESAQAFLSQHPFEELEE PHSESKDTSPKQRIQNLSRF VWKQATVASELWEKLTARCV DQHRHIERTLEQLLEIQGA |
| Tissue Specificity | Detected in fetal brain. |
| Function | Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system. |
| Protein Name | Dystrophin-Related Protein 2Drp-2 |
| Database Links | Reactome: R-HSA-9619665 |
| Cellular Localisation | Postsynaptic DensityCell ProjectionDendritePerikaryonCell MembranePeripheral Membrane ProteinDetected In Schwann Cells At Periaxonal Myelin Membranes |
| Alternative Antibody Names | Anti-Dystrophin-Related Protein 2 antibodyAnti-Drp-2 antibodyAnti-DRP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
