Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-DOG-1 is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | DOG1.1 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | Lot specific |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Synthetic peptide of human DOG1 |
Background | DOG1 is expressed ubiquitously in gastrointestinal stromal tumors irrespective of c-kit or PDGFR alpha mutation status. Reactivity for DOG1 may aid in the diagnosis of gastrointestinal stromal tumors, including PDGFRA mutants that fail to express c-kit antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the c-kit tyrosine kinase. Positive control Gastrointestinal stromal tumor tissue |
Information sourced from Uniprot.org