Anti-DOG1 antibody [DOG1.1] (STJ16101377)

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STJ16101377-6
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-DOG-1 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : DOG1.1
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tissue culture supernatant with sodium azide
Concentration: Lot specific
Storage Instruction: Store at 2-8°C for up to 1-year, upon receipt.
Immunogen: Synthetic peptide of human DOG1
Background DOG1 is expressed ubiquitously in gastrointestinal stromal tumors irrespective of c-kit or PDGFR alpha mutation status. Reactivity for DOG1 may aid in the diagnosis of gastrointestinal stromal tumors, including PDGFRA mutants that fail to express c-kit antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the c-kit tyrosine kinase. Positive control Gastrointestinal stromal tumor tissue

Information sourced from Uniprot.org